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18621-18-6 - 3-Hydroxyazetidine hydrochloride, 97% - 3-Azetidinol hydrochloride - H25842 - Alfa Aesar

H25842 3-Hydroxyazetidine hydrochloride, 97%

CAS Number
18621-18-6
Synonyms
3-Azetidinol hydrochloride

Size Price ($) Quantity Availability
250mg 26.78
1g 71.97
5g 286.20
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3-Hydroxyazetidine hydrochloride, 97%

MDL
MFCD02683887

Chemical Properties

Formula
C3H7NO•HCl
Formula Weight
109.56
Melting point
85-90°
Sensitivity
Hygroscopic
Solubility
Soluble in water, DMSO, methanol.

Applications

3-Hydroxyazetidine hydrochloride is an building block used in a recent synthesis of a fluoroquinolone antibiotic and a useful intermediate in the synthesis of polypeptides.

Notes

Hygroscopic. Store under inert gas. Store away from water/ moisture, oxidizing agents.

Literature References

Paritosh R. Dave. Acylative Dealkylation of N-tert-Butyl-3-substituted Azetidines:? Facile Access to [1.1.0]Azabicyclobutane, 3-Hydroxyazetidinium Hydrochloride, and 3-Azetidinones. J. Org. Chem. 1996, 61 (16), 5453-5455.

Stephen D. Roughley; Terance Hart. Fatty acid amide hydrolase inhibitors. 2. Novel synthesis of sterically hindered azabenzhydryl ethers and an improved synthesis of VER-156084. Tetrahedron Letters. 2010, 51 (39), 5191-5194.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2933.99
TSCA
No

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