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25991-27-9 - Methyl 2-oxo-2H-pyran-3-carboxylate, 98% - 3-Carbomethoxy-2-pyrone - 2-Oxo-2H-pyran-3-carboxylic acid methyl ester - H25932 - Alfa Aesar

H25932 Methyl 2-oxo-2H-pyran-3-carboxylate, 98%

CAS Number
25991-27-9
Synonyms
3-Carbomethoxy-2-pyrone
2-Oxo-2H-pyran-3-carboxylic acid methyl ester

Size Price ($) Quantity Availability
1g 33.00
5g 88.80
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Methyl 2-oxo-2H-pyran-3-carboxylate, 98%

MDL
MFCD00075443
EINECS
247-397-9

Chemical Properties

Formula
C7H6O4
Formula Weight
154.12
Melting point
74-77°
Boiling Point
146-148°/0.75mm

Applications

Methyl 2-oxo-2H-pyran-3-carboxylate is used as a reagent to investigate alfa, beta-unsaturated carbonyl compounds for their cytotoxic profiles against oral human normal and tumor cells.

Notes

Incompatible with strong oxidizing agents.

Literature References

Wang, H. C.; Jagtap, A. D.; Chang, P. T.; Liu, J. R.; Liu, C. P.; Tseng, H. W.; Chen, G. S.; Chern, J. W. Bioisosteric replacement of an acylureido moiety attached to an indolin-2-one scaffold with a malonamido or a 2/4-pyridinoylamido moiety produces a selectively potent Aurora-B inhibitor. Eur. J. Med. Chem. 2014, 84, 312-334.

Slack, R. D.; Siegler, M. A.; Posner, G. H. Highly stereocontrolled and regiocontrolled syntheses of polyoxygenated [2.2. 2] oxabicyclic synthons. Tetrahedron Lett. 2013, 54 (46), 6267-6270.

Other References

Beilstein
1424749
Harmonized Tariff Code
2932.99
TSCA
No

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