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4-Hydroxy-3,6-dimethyl-2-pyrone is the reactant in the formation of unnatural novel polyketides.
Terese E. Acker,; Paul E. Brenneisen,; Stuart W. Tanenbaum. Isolation, Structure, and Radiochemical Synthesis of 3,6-Dimethyl-4-hydroxy-2-pyrone. J. Am. Chem. Soc. 1966 , 88 (4), 834-837.
Ikuro Abe,; Yusuke Takahashi,; Weiwei Lou,; Hiroshi Noguchi. Enzymatic Formation of Unnatural Novel Polyketides from Alternate Starter and Nonphysiological Extension Substrate by Chalcone Synthase Org. Lett.,. 2003, 5 (8), 1277-1280.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant