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2-Fluoro-5-iodobenzoic acid is one of the precursor molecules were shown to generate ETD reagents via ESI followed by CID. Starting material in the synthesis of 3, 6-disubstituted 2-pyridinecarboxamide(GK activators).
Teng-Yi Huang,; Joshua F. Emory,; Richard A. J. O'Hair,; Scott A. McLuckey.Electron-Transfer Reagent Anion Formation via Electrospray Ionization and Collision-Induced Dissociation . Anal. Chem.,. 2006, 78 (21), 7387-7391.
Morihiro Mitsuya; Kenji Kamata; Makoto Bamba; Hitomi Watanabe; Yasuhiro Sasaki; Kaori Sasaki; Sumika Ohyama; Hideka Hosaka; Yasufumi Nagata; Jun-ichi Eiki; Teruyuki Nishimura. Discovery of novel 3,6-disubstituted 2-pyridinecarboxamide derivatives as GK activators. Bioorganic & Medicinal Chemistry Letters. 2009, 19 (10), 2718-2721.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant