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2-Fluoro-5-iodobenzoic acid is one of the precursor molecules were shown to generate ETD reagents via ESI followed by CID. Starting material in the synthesis of 3, 6-disubstituted 2-pyridinecarboxamide(GK activators).
Teng-Yi Huang,; Joshua F. Emory,; Richard A. J. O'Hair,; Scott A. McLuckey.Electron-Transfer Reagent Anion Formation via Electrospray Ionization and Collision-Induced Dissociation . Anal. Chem.,. 2006, 78 (21), 7387-7391.
Morihiro Mitsuya; Kenji Kamata; Makoto Bamba; Hitomi Watanabe; Yasuhiro Sasaki; Kaori Sasaki; Sumika Ohyama; Hideka Hosaka; Yasufumi Nagata; Jun-ichi Eiki; Teruyuki Nishimura. Discovery of novel 3,6-disubstituted 2-pyridinecarboxamide derivatives as GK activators. Bioorganic & Medicinal Chemistry Letters. 2009, 19 (10), 2718-2721.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.