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Inhibitor of protein kinase C; induces photosynthesized apoptosisHypercin acts as an antibiotic and antiviral. It is involved in the inhibition of enzyme dopamine beta-hydroxylase action. It also exhibits an anti-HIV and anticancer drug. Further, it is useful in photodynamic therapy. In addition to this, it serves as an inhibitor of protein kinase C which induces photosynthesized apoptosis.
Inhibitor of protein kinase C: Biochem Biophys. Res. Commun., 165, 1207 (1989); Photochem. Photobiol., 82, 720 (2006). Antiviral and antitumour photosensitizer: Photochem. Photobiol., 54, 95 (1991); Curr. Drug Targets, 3, 55 (2002).
Kusari, S.; Sezgin, S.; Nigutova, K.; Cellarova, E.; Spiteller, M. Spatial chemo-profiling of hypericin and related phytochemicals in Hypericum species using MALDI-HRMS imaging. Anal. Bioanal. Chem. 2015, 407 (16), 4779-4791.
Vogler, A. Fluorescence spectra of complexes of hypericin with s2 metal cations. Inorg. Chem. Commun. 2015, 54, 61-62.
Hazard Statements: H302-H317
Harmful if swallowed. May cause an allergic skin reaction.
Precautionary Statements: P261-P264b-P270-P272-P280g-P301+P312-P302+P352-P330-P333+P313-P363-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. Rinse mouth. If skin irritation or rash occurs: Get medical advice/attention. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant