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Inhibitor of protein kinase C; induces photosynthesized apoptosisHypercin acts as an antibiotic and antiviral. It is involved in the inhibition of enzyme dopamine beta-hydroxylase action. It also exhibits an anti-HIV and anticancer drug. Further, it is useful in photodynamic therapy. In addition to this, it serves as an inhibitor of protein kinase C which induces photosynthesized apoptosis.
Inhibitor of protein kinase C: Biochem Biophys. Res. Commun., 165, 1207 (1989); Photochem. Photobiol., 82, 720 (2006). Antiviral and antitumour photosensitizer: Photochem. Photobiol., 54, 95 (1991); Curr. Drug Targets, 3, 55 (2002).
Kusari, S.; Sezgin, S.; Nigutova, K.; Cellarova, E.; Spiteller, M. Spatial chemo-profiling of hypericin and related phytochemicals in Hypericum species using MALDI-HRMS imaging. Anal. Bioanal. Chem. 2015, 407 (16), 4779-4791.
Vogler, A. Fluorescence spectra of complexes of hypericin with s2 metal cations. Inorg. Chem. Commun. 2015, 54, 61-62.
Hazard Statements: H302-H317
Harmful if swallowed. May cause an allergic skin reaction.
Precautionary Statements: P261-P280g-P301+P312a-P363-P321-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves. IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Wash contaminated clothing before reuse. Specific treatment (see label). Dispose of contents/container in accordance with local/regional/national/international regulations.