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Bis(trifluoromethyl)acetophenone is used in the synthesis of the monoamine oxidase-B inhibitors. It is also used to isolate novel bacterial strain from soil samples.
Kitamura, T.; Muta, K.; Muta, K. Hypervalent Iodine-Promoted α-Fluorination of Acetophenone Derivatives with a Triethylamine·HF Complex. J. Org. Chem. 2014, 79 (12), 5842-5846.
Xiao, H.; Chai, Z.; Yao, R-S.; Zhao, G. Phosphine Catalyst-Controlled Cycloaddition or Dienylation Reactions of Trifluoromethyl Aryl Ketones with Bis-Substituted Allenoates. J. Org. Chem. 2013, 78 (19), 9781-9790.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.