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As pharmaceutical intermediate. As a metabolite of Capsaicin.
Tamara Meiresonne,; Guido Verniest,; Norbert De Kimpe,; Sven Mangelinckx. Synthesis of 2-Fluoro-1,4-benzoxazines and 2-Fluoro-1,4-benzoxazepin-5-ones by Exploring the Nucleophilic Vinylic Substitution (SNV) Reaction of gem-Difluoroenamides. J. Org. Chem. 2015 , 80 (10) ,5111-5124.
Joseph T. Repinea,; Douglas S. Johnsona,; Timothy Stuka,; Andrew D. Whitea,; Michael A. Stiera,; Tingsheng Lib,; Zhixiang Yangb,; Samarendra N. Maiti. Synthesis of fluorinated 1,8-naphthyridinone derivatives. Tetrahedron Letters. 2007, 48 46,8189-8191.
Hazard Statements: H314-H335
Causes severe skin burns and eye damage. May cause respiratory irritation.
Precautionary Statements: P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c
Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant