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H26937 (R)-(-)-3-Amino-1-Boc-piperidine, 98%

CAS Number
188111-79-7
Synonyms
(R)-Boc-3-piperidinamine
tert-Butyl (R)-3-aminopiperidine-1-carboxylate

Stock No. Size Price ($) Quantity Availability
H26937-06 5g 374.00
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(R)-(-)-3-Amino-1-Boc-piperidine, 98%

MDL
MFCD03094717

Chemical Properties

Formula
C10H20N2O2
Formula Weight
200.28
Refractive Index
1.4730
Storage & Sensitivity
Air Sensitive. Ambient temperatures.
Solubility
Immiscible with water.

Applications

(R)-(-)-3-Amino-1-Boc-piperidine is used as an intermediate in the manufacture of various substances such as pharmaceuticals.

Notes

Air and moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents and strong acids.

Literature References

Choi, H. E.; Choi, J. H.; Lee, J. Y.; Kim, J. H.; Kim, J. H.; Lee, J. K.; Kim, G. I.; Park, Y.; Chi, Y. H.; Paik, S. H.; Lee, J. H.; Lee, K. T. Synthesis and evaluation of nicotinamide derivative as anti-angiogenic agents. Bioorg. Med. Chem. Lett. 2013, 23 (7), 2083-2088.

Wang, J.; Kuryatov, A.; Jin, Z.; Norleans, J.; Kamenecka, T. M.; Kenny, P. J.; Lindstrom, J. A Novel alpha2/alpha4 Subtype-selective Positive Allosteric Modulator of Nicotinic Acetylcholine Receptors Acting from the C-tail of an alpha Subunit. J. Biol. Chem. 2015, 290 (48), 28834-28846.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Rinse mouth. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Harmonized Tariff Code
2933.39
TSCA
No

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