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(S)-3-(Boc-amino)piperidine, is used as an intermediate for pigments. It is also used as important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff. It is also an useful intermediate for the synthesis of a variety of chiral aminopiperidinyl quinolones as potent antibacterial agents against resistant pathogens; and alkynylpyrimidine amide derivatives as orally available inhibitors of Tie-2 kinase.
HK Lee.; JS Chun.; CS Pak. Facile transformation of 3, 4-disubstituted 2-azetidinones to chiral 5, 6-dihydro-2-pyridones. Tetrahedron Letters.200142 (20), 3483-3486.
XE Hu.;NK Kim.; B Ledoussal. Synthesis of trans-(3 S)-Amino-(4 R)-alkyl-and-(4 S)-Aryl-piperidines via Ring-Closing Metathesis Reaction. Organic letters.20024 (25), 4499-4502.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.