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55717-45-8 - 2-Bromo-5-hydroxypyridine, 95% - 6-Bromo-3-pyridinol - H27228 - Alfa Aesar

H27228 2-Bromo-5-hydroxypyridine, 95%

CAS Number
55717-45-8
Synonyms
6-Bromo-3-pyridinol

Size Price ($) Quantity Availability
1g 87.93
5g 228.66
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2-Bromo-5-hydroxypyridine, 95%

MDL
MFCD04114184

Chemical Properties

Formula
C5H4BrNO
Formula Weight
174.00
Melting point
133-136°
Solubility
Slightly soluble in water.

Applications

It is used as an active pharmaceutical intermediate and in the coupling reactions with halo aromatic amines and alcohols for a practical synthetic route to 2-substituted amino phenyl and hydroxyphenyl pyridines.

Notes

Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literature References

Yulin Wu, et al. 2,5-Disubstituted pyridines as potent GPR119 agonists.Bioorg. Med. Chem. Lett.,2010,20(8), 2577-2581.

Seung-Hoi Kim, et al. Coupling reactions with haloaromatic amines and alcohols for a practical synthetic route to 2-substituted aminophenyl and hydroxyphenyl pyridines.Tetrahedron Lett.,2009,50(31), 3242-46.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P280g-P305+P351+P338

Wear protective gloves. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Other References

Harmonized Tariff Code
2933.39
TSCA
No

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