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943-73-7 - L-Homophenylalanine, 98% - (S)-2-Amino-4-phenylbutyric acid - H-Homophe-OH - H27295 - Alfa Aesar

H27295 L-Homophenylalanine, 98%

CAS Number
943-73-7
Synonyms
(S)-2-Amino-4-phenylbutyric acid
H-Homophe-OH

Size Price ($) Quantity Availability
1g 58.50
5g 174.00
25g 551.00
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L-Homophenylalanine, 98%

MDL
MFCD00002619
EINECS
213-403-3

Chemical Properties

Formula
C10H13NO2
Formula Weight
179.22
Melting point
>300°
Solubility
Soluble in dilute aqueous acid.

Applications

L-Homophenylalanine is used as a precursor in the pharmaceutical industry for the production of angiotensin-converting enzyme (ACE) and R-(-)-Homophenylalanin-ethylester. It is also involved in the synthesis of NEPA [(S,S)-N-(1-Ethoxycarbonyl-3-phenylpropyl)alanine], which is a key intermediate to prepare the ACE-inhibitors: enalapril, delapril, quinapril and ramipril. It acts as an anti-tumor reagent.

Notes

Store in cool place. Incompatible with strong oxidizing agents, strong acids and bases.

Literature References

Zhang, J.; Tao, S.; Zhang, B.; Wu, X.; Chen, Y. Microparticle-based strategy for controlled release of substrate for the biocatalytic preparation of L-homophenylalanine. ACS Catal. 2014, 4 (5), 1584-1587.

Zhang, J.; Zhu, T.; Wu, X.; Chen, Y. Enhancement of biocatalytic efficiency by increasing substrate loading: enzymatic preparation of L-homophenylalanine. Appl. Microbiol. Biotechnol. 2013, 97 (19), 8487-8494.

Other References

Harmonized Tariff Code
2922.49
TSCA
No

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