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3-Maleimidopropionic acid N-hydroxysuccinimide ester is a reagent that is widely used for generating stable maleimide-activated carrier proteins that can spontaneously react with sulfhydryls. Alternatively these relatively stable maleimide-activated intermediates may be lyophilized and stored for later conjugation to a hapten.
Kleanthis G. Dendrinos,; Aristotle G. Kalivretenos. Synthesis of N-hydroxysuccinimide esters using polymer bound HOBT. Tetrahedron Letters. 1998, 39(11), 1321-1324.
Wlad Kusnezow,; Anette Jacob,; Alexandra Walijew,; Frank Diehl,;örg D. Hoheisel. Antibody microarrays: An evaluation of production parameters. PROTEOMICS. 2003, 33, 254-264,.
Sulfhydryl- (SH) and amino-reactive heterobifunctional cross-linking agent: Enzym. Immunoassay, 81 (1981); J. Immunol. Meth., 62, 123 (1983). Applications in immunodiagnostics: Biopolymers, 22, 481 (1983).
Hazard Statements: H335
May cause respiratory irritation.
Precautionary Statements: P261-P271-P304+P340-P312-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Use only outdoors or in a well-ventilated area. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Call a POISON CENTER or doctor/physician if you feel unwell. Dispose of contents/ container to an approved waste disposal plant