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As active pharmaceutical drugs and intermediates possess different biological activities.
Chia-Yu Huanga,; Tara M. Stauffera,; Corey L. Stricklandb,; John C. Readera,; He Huanga,; Ge Lia,; Alan B. Cooperb,; Ronald J. Dollb,; Ashit K. Gangulyb,; John J. Baldwina,; Laura L. Rokosz. Guiding farnesyltransferase inhibitors from an ECLiPS® library to the catalytic zinc. Bioorganic & Medicinal Chemistry Letters. 2006, 16 (3),507-511.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant