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4-Amino-2-nitrophenol was used in determination of aminonitrophenols in hair dyes by differential pulse voltammetry and HPLC with electrochemical detection. It is commonly used as semipermanent (nonoxidative) hair colorant and toner in permanent (oxidative) hair dye products.
T.A. Robert .; A.N. Hagardorn. Plasma levels and kinetic disposition of 2,4-dinitrophenol and its metabolites 2-amino-4-nitrophenol and 4-amino-2-nitrophenol in the mouse.J. Chromatogr. B. 1985, 344 177-186.
Hazard Statements: H302-H312-H315-H318-H341-H335
Harmful if swallowed. Harmful in contact with skin. Causes skin irritation. Causes serious eye damage. Suspected of causing genetic defects. May cause respiratory irritation.
Precautionary Statements: P280-P305+P351+P338-P337+P313
Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice/attention.