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H27697 5-Methyl-2-furoyl chloride, 97%

CAS Number
5-Methylfuran-2-carbonyl chloride

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5-Methyl-2-furoyl chloride, 97%


Chemical Properties

Formula Weight
Melting point
Flash Point
Storage & Sensitivity
Keep Cold. Moisture Sensitive.
Reacts with water.


As pharmaceutical intermediates and reagent. In chemical research. The intermediate 2-halo- acetylfurans (chloro or bromo) were obtained by a hazardous procedure involving the treatment of 2-furoylchloride (highly lachrymatory) with diazomethane followed by the decomposition of the intermediate with dry HCl. Three monoprotic tridentate ligands were synthesized by condensation of 2-furoylchloride with anthranilic acid and β-alanine, and 2-acetylpyridine with orthanilic acid.


Highly lachrymatory. Moisture Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, bases, water, moisture.

Literature References

Shiv P. Singh,; Rajesh Naithani,; Ranjana Aggarwal,; Om Prakash. A Convenient Synthesis of 4-(2-Furyl)-2-substituted Thiazoles Utilising [Hydroxy(tosyloxy)iodo]benzene. Synthetic Communications: An International Journal for Rapid Communication of Synthetic Organic Chemistry. 1998, 28 (13), 2371-2378.

Gehad G. Mohamed,; M.M. Omar,; Ahmed M.M. Hindy.Three monoprotic tridentate ligands were synthesized by condensation of 2-furoylchloride with anthranilic acid and β-alanine, and 2-acetylpyridine with orthanilic acid. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2005, 62(4-5), 1140-1150.

AL Mndzhoian. 5-Methyl-2-Furoyl Chloride. Syntheses of Heterocyclic Compounds. 1959 , volume 57-58.

GHS Hazard and Precautionary Statements

Hazard Statements: H314-H335

Causes severe skin burns and eye damage. May cause respiratory irritation.

Precautionary Statements: P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c

Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

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Harmonized Tariff Code


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