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As pharmaceutical intermediates and reagent. In chemical research. The intermediate 2-halo- acetylfurans (chloro or bromo) were obtained by a hazardous procedure involving the treatment of 2-furoylchloride (highly lachrymatory) with diazomethane followed by the decomposition of the intermediate with dry HCl. Three monoprotic tridentate ligands were synthesized by condensation of 2-furoylchloride with anthranilic acid and β-alanine, and 2-acetylpyridine with orthanilic acid.
Shiv P. Singh,; Rajesh Naithani,; Ranjana Aggarwal,; Om Prakash. A Convenient Synthesis of 4-(2-Furyl)-2-substituted Thiazoles Utilising [Hydroxy(tosyloxy)iodo]benzene. Synthetic Communications: An International Journal for Rapid Communication of Synthetic Organic Chemistry. 1998, 28 (13), 2371-2378.
Gehad G. Mohamed,; M.M. Omar,; Ahmed M.M. Hindy.Three monoprotic tridentate ligands were synthesized by condensation of 2-furoylchloride with anthranilic acid and β-alanine, and 2-acetylpyridine with orthanilic acid. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2005, 62(4-5), 1140-1150.
AL Mndzhoian. 5-Methyl-2-Furoyl Chloride. Syntheses of Heterocyclic Compounds. 1959 , volume 57-58.
Hazard Statements: H314-H318
Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P260u-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.