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4-Cyanopiperidine is used as an intermediate for the preparation of pharmaceutical substances like antidepressants and anti-inflammatory. It is used as a precursor for the synthesis of piperidine derivatives.
Tran, L. D.; Roane, J.; Daugulis, O. Directed Amination of Non-Acidic Arene C[BOND]H Bonds by a Copper-Silver Catalytic System. Angew. Chem. Int. Ed. 2013, 52 (23), 6043-6046.
Woo, H. M.; Lee, Y. S.; Roh, E. J.; Seo, S. H.; Song, C. M.; Chung, H. J.; Pae, A. N.; Shin, K. J. Synthesis and biological evaluation of 4-piperidinecarboxylate and 4-piperidinecyanide derivatives for T-type calcium channel blockers. Bioorg. Med. Chem. Lett. 2011, 21 (19), 5910-5915.
Hazard Statements: H302-H311-H315-H318-H331
Harmful if swallowed. Toxic in contact with skin. Causes skin irritation. Causes serious eye damage. Toxic if inhaled.
Precautionary Statements: P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P310-P311-P312-P330-P332+P313-P361-P363-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Call a POISON CENTER or doctor/physician. Rinse mouth. If skin irritation occurs: Get medical advice/attention. Remove/Take off immediately all contaminated clothing. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant