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79-55-0 - 1,2,2,6,6-Pentamethylpiperidine, 97% - Pempidine - PMP - H27729 - Alfa Aesar

H27729 1,2,2,6,6-Pentamethylpiperidine, 97%

CAS Number
79-55-0
Synonyms
Pempidine
PMP

Size Price ($) Quantity Availability
1g 29.97
5g 72.10
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1,2,2,6,6-Pentamethylpiperidine, 97%

MDL
MFCD00006493
EINECS
201-211-2

Chemical Properties

Formula
C10H21N
Formula Weight
155.28
Boiling Point
187-188°
Flash Point
50°(122°F)
Density
0.858
Sensitivity
Air Sensitive
Solubility
Soluble in toluene, dimethylformamide.

Applications

Pharmacological evaluation of the antagonism of nicotine's central effects by mecamylamine and pempidine where pempidine was found to increase the ED50 of nicotine (0.73 mg/kg) for depression of spontaneous activity in a dose-related manner. At a dose of 3 mg/kg, pempidine increased nicotine's ED50 4.7-fold.

Notes

Air Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, air.

Literature References

T J Martin,; J Suchocki,; E L May,; B R Martin. Pharmacological evaluation of the antagonism of nicotine's central effects by mecamylamine and pempidine. . JPET. 1994, 254 (1), 45-51.

authors. title . Journal name. year of publication , volume issue , pg no.

GHS Hazard and Precautionary Statements

Hazard Statements: H226-H302-H315-H319-H335

Flammable liquid and vapour. Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P210-P261-P280-P240-P303+P361+P353-P305+P351+P338-P304+P340-P362-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Ground/bond container and receiving equipment. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,7080
Beilstein
103806
Hazard Class
3
Packing Group
III
Harmonized Tariff Code
2933.39
TSCA
Yes
RTECS
TN2190000

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