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80875-98-5 - (2S,3aS,7aS)-Octahydroindole-2-carboxylic acid, 98% - H27894 - Alfa Aesar

H27894 (2S,3aS,7aS)-Octahydroindole-2-carboxylic acid, 98%

CAS Number

Size Price ($) Quantity Availability
1g 69.10
5g 203.00
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(2S,3aS,7aS)-Octahydroindole-2-carboxylic acid, 98%


Chemical Properties

Formula Weight
Melting point
266° dec.
Optical Rotation
-50 (c=1 in methanol)
Soluble in methanol and water.


An intermediate in the synthesis of Perindopril. The completely diastereoselective α-alkylation of oxazolidinone provides a very convenient and concise route to enantiopure α-tetrasubstituted derivatives of this Oic stereoisomer.


Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents. Store at -20°C.

Literature References

Francisco J. Sayago,; M. Isabel Calaza,; Ana I. Jiménez,; Carlos Cativiela. A straightforward route to enantiopure α-substituted derivatives of (2S,3aS,7aS)-octahydroindole-2-carboxylic acid. Journal name. 2009, 65(27) ,5174-5180.

Francisco J. Sayago,; M. Isabel Calaza,; Ana I. Jiménez,; Carlos Cativiela. Versatile methodology for the synthesis and α-functionalization of (2R,3aS,7aS)-octahydroindole-2-carboxylic acid. Tetrahedron. 2008, 64(1), 84-91.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code


  • A17629

    Sodium thiosulfate, anhydrous, 99%
  • B25745

    4,16-Dibromo[2.2]paracyclophane, 98%

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