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100846-24-0 - 5-(Trifluoromethyl)indole, 98% - H28782 - Alfa Aesar

H28782 5-(Trifluoromethyl)indole, 98%

CAS Number

Size Price ($) Quantity Availability
100mg 112.00
500mg 343.00
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5-(Trifluoromethyl)indole, 98%


Chemical Properties

Formula Weight
Melting point


In 3-Naphthylindole construction by rhodium (II)-catalyzed regioselective direct arylation of indoles with 1-diazonaphthalen-2-(1H)-ones treatment of 5-(trifluoromethyl)indole(1k) or 6-(trifluoromethyl)indole (1l) with 2a afforded the desired products 3k (86%)and 3l (86%).


Light Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, light.

Literature References

Ek Raj Baral,; Yong Rok Lee1,; Sung Hong Kim2. 3-Naphthylindole Construction by Rhodium(II)-Catalyzed Regioselective Direct Arylation of Indoles with 1-Diazonaphthalen-2-(1H)-ones. Advanced Synthesis & Catalysis. 2015, 357 (13),2883-2892.

Larisa V. Politanskaya,; Igor P. Chuikov,; Vitalij D. Shteingarts. Synthesis of indoles with a polyfluorinated benzene ring . Tetrahedron. 2013 , 69 (39),8477-8486.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code


  • B25683

    Methyl 4-fluoro-3-hydroxybenzoate, 98+%
  • H33193

    Methyl 4-iodopyrrole-2-carboxylate, 97%

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