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1-Adamantanamine acts as a catalyst in enantioselective strecker reaction of phosphinoyl imines. It is also useful for making adamantane derivatives, i.e. amantadine hydrochloride. It is used in the pharmaceutical industry as antiviral and an antiparkinsonian drug.
Yang, H.; Liu, Y.; Yang, L.; Liu, K.; Wang, Z.; Zhang, X. Cucurbituril as a "protective agent": controlling photochemistry and detecting 1-adamantanamine. Chem. Commun. 2013, 49, 3905-3907.
Bose, A.; Das, J. K.; Das, N. Pore modification of deca-dodecasil-rhombohedral zeolite membrane by carbon loading from in situ decomposition of 1-adamantanamine for improved gas separation. RSC Adv. 2015, 5, , 67195-67205.
Hazard Statements: H302-H315-H319-H335
Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.