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Decarboxylative cross-coupling of thiazole and oxazole-5-carboxylic acids with aryl halides is reported.
J. W. Cornforth,; R. H. Cornforth, Mrs. Synthesis of oxazoles from ethyl acetoacetate. Ring-fission of some oxazole-5-carboxylic acids. J. Chem. Soc. 1953, volume 93-98.
Fengzhi Zhang,; Michael F. Greany. Decarboxylative Cross-Coupling of Azoyl Carboxylic Acids with Aryl Halides. Org. Lett. 2010, 12 (21), 4745-4747.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.