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H30179 Oxazole-5-carboxylic acid, 98+%

CAS Number
118994-90-4
Synonyms
Oxazole-5-carboxylic acid
5-Carboxy-1,3-oxazole

Stock No. Size Price ($) Quantity Availability
H30179-03 1g 50.00
H30179-06 5g 164.00
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Oxazole-5-carboxylic acid, 98+%

MDL
MFCD04114931

Chemical Properties

Formula
C4H3NO3
Formula Weight
113.07
Melting point
ca 245° dec.
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in water.

Applications

Decarboxylative cross-coupling of thiazole and oxazole-5-carboxylic acids with aryl halides is reported.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Literature References

J. W. Cornforth,; R. H. Cornforth, Mrs. Synthesis of oxazoles from ethyl acetoacetate. Ring-fission of some oxazole-5-carboxylic acids. J. Chem. Soc. 1953, volume 93-98.

Fengzhi Zhang,; Michael F. Greany. Decarboxylative Cross-Coupling of Azoyl Carboxylic Acids with Aryl Halides. Org. Lett. 2010, 12 (21), 4745-4747.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Harmonized Tariff Code
2934.99
TSCA
No

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