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H30538 (S)-(+)-3-Amino-1-Boc-piperidine, 97%

CAS Number
tert-Butyl (R)-3-aminopiperidine-1-carboxylate

Stock No. Size Price ($) Quantity Availability
H30538-MD 250mg 65.30
H30538-03 1g 180.00
H30538-06 5g 600.00
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(S)-(+)-3-Amino-1-Boc-piperidine, 97%


Chemical Properties

Formula Weight
Storage & Sensitivity
Air Sensitive. Ambient temperatures.
Soluble in dimethylsulfoxide.


(S)-(+)-3-Amino-1-Boc-piperidine is used to prepare selective noncovalent inhibitors of the bacterial cysteine protease IdeS. The product obtained by the reductive elimination reaction with ethylglyoxalte is used as a reference compound, which is used to determine the absolute configuration of the two enantiomers.


Air and carbon dioxide sensitive. Incompatible with strong oxidizing agents, strong acids and bases. Store in a cool place.

Literature References

Berggren, K.; Vindebro, R.; Bergstro?m, C.; Spoerry, C.; Persson, H.; Fex, T.; Kihlberg, J.; Rammingen, U. V. P.; Luthman, K. 3-Aminopiperidine-Based Peptide Analogues as the First Selective Noncovalent Inhibitors of the Bacterial Cysteine Protease IdeS. J. Med. Chem. 2012, 55 (6), 2549-2560.

Henary, M.; Paranjpe, S.; Owens, E. A. Substituted benzothiazoles: synthesis and medicinal characteristics. Heterocycl. Commun. 2013, 19 (2), 89-99.

GHS Hazard and Precautionary Statements

Hazard Statements: H314-H335

Causes severe skin burns and eye damage. May cause respiratory irritation.

Precautionary Statements: P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c

Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Hazard Class
Packing Group
Harmonized Tariff Code


  • H26937

    (R)-(-)-3-Amino-1-Boc-piperidine, 98%
  • H27700

    (S)-(+)-3-Aminopiperidine dihydrochloride, 98%
  • H28218

    1-Boc-3-aminoazetidine, 94%
  • H30779

    4-Amino-1-Boc-piperidine, 97%

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