H30779 4-Amino-1-Boc-piperidine, 97%
SDS
| Stock No. | Size | Price ($) | Quantity | Availability |
|---|---|---|---|---|
| H30779-03 | 1g | 53.70 |
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| H30779-06 | 5g | 152.00 |
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4-Amino-1-Boc-piperidine, 97%
Chemical Properties
Applications
4-Amino-1-Boc-piperidine is a chemical reagent used in the preparation of pharmaceutical compounds. Used in the synthesis of bromodomain inhibitors as well as HepG2 cell cycle inhibitors used in anti-tumor therapy. Also employed in a microwave-assisted solid-phase synthesis of N-substituted piperidines via direct annulation of primary amines with resin-bound dimesylates.
Notes
Literature References
Calum Macleod; Blanca I Martinez-Teipel; William M Barker; Roland E Dolle. Annulation of primary amines to piperazines and diazaspirocycles utilizing alpha-methyl benzyl resin. Journal of Combinatorial Chemistry,2006, 8(1), 132-140.
Demont, E. et al. Fragment-Based Discovery of Low-Micromolar ATAD2 Bromodomain Inhibitors. J. Med. Chem,2015, 58 (14), 5649-5673.
GHS Hazard and Precautionary Statements
Hazard Statements: H314-H318
Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P280-P305+P351+P338-P309-P310a
Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or if you feel unwell: Immediately call a POISON CENTER/doctor
