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81290-20-2 - (Trifluoromethyl)trimethylsilane, 0.5M soln. in THF - H31520 - Alfa Aesar

H31520 (Trifluoromethyl)trimethylsilane, 0.5M soln. in THF

CAS Number
81290-20-2
Synonyms

Size Price ($) Quantity Availability
5ml 23.60
25ml 76.80
100ml 220.00
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(Trifluoromethyl)trimethylsilane, 0.5M soln. in THF

MDL
MFCD00145454

Chemical Properties

Formula
C4H9F3Si
Formula Weight
142.20
Boiling Point
40°
Flash Point
17°(63°F)
Density
0.895
Sensitivity
Moisture Sensitive
Solubility
Hydrolyzes in water.

Applications

A reagent used in nucleophilic addition of the trifluoromethyl group to aldehydes and ketones.

Notes

Moisture Sensitive. Store away from oxidizing agents, water/ moisture.

Literature References

G K Surya Prakash; Chiradeep Panja; Habiba Vaghoo; Vijayalakshmi Surampudi; Roman Kultyshev; Mihirbaran Mandal; Golam Rasul; Thomas Mathew; George A Olah. Facile synthesis of TMS-protected trifluoromethylated alcohols using trifluoromethyltrimethylsilane (TMSCF3) and various nucleophilic catalysts in DMF. Journal of Organic Chemistry. 2006, 71 (18), 6806-6813.

Rajendra P. Singh; Ganfeng Cao; Robert L. Kirchmeier and Jean'ne M. Shreeve. Cesium Fluoride Catalyzed Trifluoromethylation of Esters, Aldehydes, and Ketones with (Trifluoromethyl)trimethylsilane. J. Org. Chem. 1999, 64 (8), 2873-2876.

GHS Hazard and Precautionary Statements

Hazard Statements: H225-H351-H319-H335

Highly flammable liquid and vapour. Suspected of causing cancer. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P210-P201-P261-P280-P281-P303+P361+P353-P305+P351+P338-P304+P340-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Obtain special instructions before use. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Use personal protective equipment as required. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Hazard Class
3
Packing Group
II
Harmonized Tariff Code
2931.90
TSCA
No

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