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The propionanilide derivatives are the first developed non-steroidal antiandrogens and include drugs such as flutamide, hydroxyflutamide, nilutamide and bicalutamide.
E. C. Gilbert,; Loyal Clarke. A Study of the system: Acetanilide-Propionanilide. J. Am. Chem. Soc. 1927, 49 (9),2296-2299.
Y. Nawata, Y. Katoh,; M. Takagi,; K. Ochi. Structure of propionanilide derivative AN132. Acta Cryst. 1987, 43 2462-2463.
Hazard Statements: H302
Harmful if swallowed.
Precautionary Statements: P280f
Wear protective clothing.