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H32103 2-Fluoro-5-(trifluoromethoxy)aniline, 97%

CAS Number
116369-23-4
Synonyms

Stock No. Size Price ($) Quantity Availability
H32103-03 1g 118.00
H32103-06 5g 476.00
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2-Fluoro-5-(trifluoromethoxy)aniline, 97%

MDL
MFCD09832254

Chemical Properties

Formula
C7H5F4NO
Formula Weight
195.12
Refractive Index
1.4485
Storage & Sensitivity
Ambient temperatures.
Solubility
Insoluble in water.

Applications

In discovery of novel benzimidazoles as potent inhibitors of TIE-2 and VEGFR-2 tyrosine kinase receptors 2-Fluoro-5-(trifluoromethoxy)aniline is used as coupling agent. 2-Fluoro-5-(trifluoromethyl)aniline may be used in chemical synthesis studies.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Literature References

Masaki Setoh,; Naoki Ishii,; Mitsunori Kono,; Yuhei Miyanohana,; Eri Shiraish,; Toshiya Harasawa,; Hiroyuki Ota,; Tomoyuki Odani,; Naoyuki Kanzaki,; Kazunobu Aoyama,; Teruki Hamada,; Masakuni Kori. Discovery of the First Potent and Orally Available Agonist of the Orphan G-Protein-Coupled Receptor 52. J. Med. Chem. 2014 , 57(12) ,5226-5237.

authors. title . Journal name. year of publication , volume issue , pg no.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H311-H315-H319-H332

Harmful if swallowed. Toxic in contact with skin. Causes skin irritation. Causes serious eye irritation. Harmful if inhaled.

Precautionary Statements: P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P361-P363-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Rinse mouth. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Remove/Take off immediately all contaminated clothing. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Hazard Class
6.1
Packing Group
III
Harmonized Tariff Code
2922.29
TSCA
No

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