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116369-23-4 - 2-Fluoro-5-(trifluoromethoxy)aniline, 97% - H32103 - Alfa Aesar

H32103 2-Fluoro-5-(trifluoromethoxy)aniline, 97%

CAS Number
116369-23-4
Synonyms

Size Price ($) Quantity Availability
1g 127.00
5g 510.00
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2-Fluoro-5-(trifluoromethoxy)aniline, 97%

MDL
MFCD09832254

Chemical Properties

Formula
C7H5F4NO
Formula Weight
195.12
Refractive Index
1.4485
Solubility
Insoluble in water.

Applications

In discovery of novel benzimidazoles as potent inhibitors of TIE-2 and VEGFR-2 tyrosine kinase receptors 2-Fluoro-5-(trifluoromethoxy)aniline is used as coupling agent. 2-Fluoro-5-(trifluoromethyl)aniline may be used in chemical synthesis studies.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Literature References

Masaki Setoh,; Naoki Ishii,; Mitsunori Kono,; Yuhei Miyanohana,; Eri Shiraish,; Toshiya Harasawa,; Hiroyuki Ota,; Tomoyuki Odani,; Naoyuki Kanzaki,; Kazunobu Aoyama,; Teruki Hamada,; Masakuni Kori. Discovery of the First Potent and Orally Available Agonist of the Orphan G-Protein-Coupled Receptor 52. J. Med. Chem. 2014 , 57(12) ,5226-5237.

authors. title . Journal name. year of publication , volume issue , pg no.

GHS Hazard and Precautionary Statements

Hazard Statements: H311-H302-H332-H315-H319

Toxic in contact with skin. Harmful if swallowed. Harmful if inhaled. Causes skin irritation. Causes serious eye irritation.

Precautionary Statements: P280h-P305+P351+P338-P309-P310-P302+P352

Wear protective gloves/clothing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or if you feel unwell: Immediately call a POISON CENTER or doctor/physician. IF ON SKIN: Wash with plenty of soap and water.

Other References

Hazard Class
6.1
Packing Group
III
Harmonized Tariff Code
2922.29
TSCA
No

Recommended

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    4-Chloro-3-(trifluoromethoxy)aniline, 97%
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