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H32280 4-Methoxy-2-(trifluoromethyl)benzenesulfonyl chloride, 97%

CAS Number
775288-85-2
Synonyms

Stock No. Size Price ($) Quantity Availability
H32280-MD 250mg 48.80
H32280-03 1g 162.00
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4-Methoxy-2-(trifluoromethyl)benzenesulfonyl chloride, 97%

MDL
MFCD11519323

Chemical Properties

Formula
C8H6ClF3O3S
Formula Weight
274.64
Melting point
57-60°
Storage & Sensitivity
Moisture Sensitive. Store under Nitrogen. Ambient temperatures.
Solubility
Insoluble in water.

Applications

4-Methoxy-2-(trifluoromethyl)benzenesulfonyl chloride, is used as a pharmaceutical intermediate.

Notes

Moisture Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Stable under recommended storage conditions. Keep away from strong oxidizing agents, bases.

Literature References

N Primas.; P Verhaeghe.; A Cohen.; C Kieffer.; A Dumètre. A New Synthetic Route to Original Sulfonamide Derivatives in 2-Trichloromethylquinazoline Series: A Structure-Activity Relationship Study of Antiplasmodial Activity. Molecules. 201213 (2), 2404-2408.

J Karl.; R Gust.; T Spruss.; MR Schneider. Ring-substituted [1, 2-bis (4-hydroxyphenyl) ethylenediamine] dichloroplatinum (II) complexes: compounds with a selective effect on the hormone-dependent mammary carcinoma . J. Med. Chem. 198831 (1), 72-83.

GHS Hazard and Precautionary Statements

Hazard Statements: H314-H335

Causes severe skin burns and eye damage. May cause respiratory irritation.

Precautionary Statements: P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c

Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Hazard Class
8
Packing Group
II
Harmonized Tariff Code
2909.30
TSCA
No

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