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394-04-7 - 5-Fluoro-2-methoxybenzoic acid, 97% - H32389 - Alfa Aesar

H32389 5-Fluoro-2-methoxybenzoic acid, 97%

CAS Number

Size Price ($) Quantity Availability
1g 81.60
5g 380.70
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5-Fluoro-2-methoxybenzoic acid, 97%


Chemical Properties

Formula Weight
Melting point
Insoluble in water.


5-Fluoro-3-hydroxy-2-methylbenzoic acid 1 was synthesized from 5-fluoro-2-methylbenzoic acid by nitration, reduction, diazotization and hydrolysis. Another methylcarbamoyl-substituted benzylamine 12 was synthesized from 5-fluoro-2-methylbenzoic acid via the sequential bromination,azido replacement and the reduction.


Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Literature References

Eiji Takashiro,; Ichiro Hayakawa,; Tamayo Nitta,; Atsushi Kasuya,; Shuichi Miyamoto,; Yuji Ozawa,; Ryuichi Yagi,; Ikue Yamamoto,; Takahiro Shibayama,; Akihiko Nakagawa,; Yuichiro Yabe. Structure-activity relationship of HIV-1 protease inhibitors containing α-hydroxy-β-amino acids. Detailed study of P1 site. Bioorganic & Medicinal Chemistry. 1999, 7(9),2063-2072.

Xing Fana,; Feng-Hua Zhanga,; Rasha I. Al-Safi,; Li-Fan Zenga,; Yumna Shabaik,; Bikash Debnath,; Tino W. Sanchez,; Srinivas Odde,; Nouri Neamati,; Ya-Qiu Long. Design of HIV-1 integrase inhibitors targeting the catalytic domain as well as its interaction with LEDGF/p75: A scaffold hopping approach using salicylate and catechol groups. Bioorganic & Medicinal Chemistry. 2011, 19(16), 4935-4952.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P280g-P305+P351+P338

Wear protective gloves. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Other References

Harmonized Tariff Code


  • J63871

    G418 disulfate, 50mg/ml solution
  • H50243

    3-Chloromethyl-5-(3-methoxyphenyl)-1,2,4-oxadiazole, 99%
  • A12172

    4-Isopropylbenzyl alcohol, tech. 90%
  • 44349

    Indium(III) chloride, ultra dry, 99.999% (metals basis)
  • H52605

    2-Fluoro-5-(isopropylcarbamoyl)benzeneboronic acid, 98%

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