Tri-n-butylborane is used as a reactant for addition reactions for synthesis of phenyltrialkylborate salts, boron-based multicomponent reactions for generation of substituted aziridines, oxazolidines, and pyrrolidines, Suzuki-Miyaura cross coupling of halopurines with trialkylboranes for the synthesis of adenosine A2A receptor antagonists, multicomponent C-alkylation reactions with aromatic aldimines, one-pot alkylation-boration and electrophilic substitution.
Masuhiro Tsukada.; Takashi Yamamoto.; Nobuo Nakabayashi.; Hiroshi Ishikawa.; Giuliano Freddi. Grafting of methyl methacrylate onto silk fibers initiated by tri-n-butylborane. Journal of Applied Polymer Science. 1991, 43 (11), 2115-2121.
Hideo Matsumura.; Takuo Tanaka.; Yohsuke Taira.; Mitsuru Atsuta. Bonding of a cobalt-chromium alloy with acidic primers and tri-n-butylborane-initiated luting agents. The Journal of Prosthetic Dentistry. 1996, 76 (2), 194-199.
Hazard Statements: H225-H302-H333-H319-H351-H335
Highly flammable liquid and vapour. Harmful if swallowed. May be harmful if inhaled. Causes serious eye irritation. Suspected of causing cancer. May cause respiratory irritation.
Precautionary Statements: P210-P201-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Obtain special instructions before use. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.