Ethyl 2-bromo-4,4,4-trifluorobutyrate is used as a pharmaceutical intermediate.
Pin Wang.; Yi Tang.; David A. Incorporation of Trifluoroisoleucine into Proteins in Vivo. J. Am. Chem. Soc. 2003, 125 (23), 6900-6906.
H. M. Walborsky.; M. Baum.; D. F. Loncrini. The Syntheses of ?-Trifluoromethyl Amino Acids. II.1,2 Their Microbiological Activities. J. Am. Chem. Soc. 1955, 77 (13), 3637-3640.
Hazard Statements: H314-H335
Causes severe skin burns and eye damage. May cause respiratory irritation.
Precautionary Statements: P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c
Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant