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177735-28-3 - 2,5-Dichlorothiophene-3-boronic acid, 95% - H32803 - Alfa Aesar

H32803 2,5-Dichlorothiophene-3-boronic acid, 95%

CAS Number
177735-28-3
Synonyms

Size Price ($) Quantity Availability
250mg 107.58
1g 170.17
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2,5-Dichlorothiophene-3-boronic acid, 95%

MDL
MFCD09837622

Chemical Properties

Formula
C4H3BCl2O2S
Formula Weight
196.85

Applications

Used in suzuki-miyaura coupling reaction. The palladium-catalyzed coupling reaction of arylboronicacids with ethyl glyoxylate provides a straightforward method for the synthesis of mandelic esters. Mandelic esters were isolated in good-to-excellent yields with a variety of neutral, slightly electron-rich, and slightly electron-poor substituents.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, heat.

Literature References

Zhongyu Duan,; Sadananda Ranjit,; Xiaogang Liu. One-Pot Synthesis of Amine-Substituted Aryl Sulfides and Benzo[b]thiophene Derivatives. Org. Lett., 2010, 12 (10), 2430-2433.

Irene Notar Francesco,; Alain Wagner,; Françoise Colobert. Suzuki-Miyaura Coupling Reaction of Boronic Acids and Ethyl Glyoxylate: Synthetic Access to Mandelate Derivatives. European Journal of Organic Chemistry. 2008, 34 issue , 5692-5695.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2934.99
TSCA
No

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