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53981-24-1 - 2-Amino-5-fluorophenol, 97% - 2-Hydroxy-4-fluoroaniline - H32928 - Alfa Aesar

H32928 2-Amino-5-fluorophenol, 97%

CAS Number
53981-24-1
Synonyms
2-Hydroxy-4-fluoroaniline

Size Price ($) Quantity Availability
250mg 60.10
1g 169.00
5g 562.00
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2-Amino-5-fluorophenol, 97%

MDL
MFCD00671759

Chemical Properties

Formula
C6H6FNO
Formula Weight
127.12
Melting point
135-140°
Sensitivity
Air Sensitive
Solubility
Slightly soluble in water.

Applications

2-Amino-5-fluorophenol is a fluoroaniline metabolite. 2-Amino-5-fluorophenol is used as organic intermediate. To synthesize the intermediate (2-amino-5-fluorophenol-N, N, O-triacetic acid trimethyl ester) of indicator which used in the determination Mg2+ by NMR, three feasible reactions were experimentally carried out, such as alkaline hydrolysis, catalytic hydrogenation and esterification.

Notes

Air Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents. Refrigerated.

Literature References

QIAO Juan,; HUANG Rongqing,; XIAO Bingkun,; LUO Chuanhuan,; ZHANG Hongyi,; XIE Huijun. Synthesis of 2-Amino-5-fluorophenol-N, N, O-triacetic Acid Trimethyl Ester. Science Technology and Engineering. 2004,

Raimund Peter,; Ronald Boecker,; Philippe H. Beaune,; Masahiko Iwasaki,; F. Peter Guengerich,; Chung S. Yang. Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P-450IIE1. Chem. Res. Toxicol. 1990, 3(6), 566-573.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H312-H315-H319-H335

Harmful if swallowed. Harmful in contact with skin. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P280h-P305+P351+P338-P312a

Wear protective gloves/clothing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER/doctor if you feel unwell.

Other References

Harmonized Tariff Code
2922.29
TSCA
No

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