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261635-93-2 - 2-Methyl-6-(trifluoromethyl)nicotinic acid, 97% - 2-Methyl-6-(trifluoromethyl)pyridine-3-carboxylic acid - H33003 - Alfa Aesar

H33003 2-Methyl-6-(trifluoromethyl)nicotinic acid, 97%

CAS Number
2-Methyl-6-(trifluoromethyl)pyridine-3-carboxylic acid

Size Price ($) Quantity Availability
1g 47.38
10g 312.80
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2-Methyl-6-(trifluoromethyl)nicotinic acid, 97%


Chemical Properties

Formula Weight
Melting point
Slightly soluble in water (4.7 g/L at 25°C).


2-Methyl-6-(trifluoromethyl)nicotinic acid is used as a pharmaceutical intermediate.


Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents.

Literature References

Kirk D. Robarge.; Shirley A. Brunton.; Georgette M. Castanedo.; Yong Cuia, Michael S. Dina.; Richard Goldsmith.; Stephen E. Gould.; Oivin Guichert.; Janet L. Gunzner.; Jason Halladay.; Wei Jia.; Cyrus Khojasteh.; Michael F.T. Koehlera, Karen Kotkowc, Hank Laa, Rebecca L. LaLondea, Kevin Lau.; Leslie Lee.; Derek Marshall.; James C. Marsters Jr.; Lesley J. Murray.; Changgeng Qian.; Lee L. Rubin.; Laurent Salphati.; Mark S. Stanley.; John H.A. Stibbard.; Daniel P. Sutherlin.; Savita Ubhayaker.; Shumei Wang.; Susan Wong.; Minli Xie. GDC-0449—A potent inhibitor of the hedgehog pathway. Bioorganic & Medicinal Chemistry Letters. 2009, 19 (19), 5576-5581.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

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