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2-Methyl-4-(trifluoromethoxy)benzaldehyde is suitable for use in the synthesis of (E)-4-(trifluoromethoxy)benzaldehyde thiosemicarbazone. It is also used in the synthesis of new azo dyes containing of 5(4H)-oxazolone ring, 2-[4-(trifluoromethoxy)phenyl]-1H-benzimidazole and (E)-2-[4-(trifluoromethoxy)benzylidene]indan-1-one.
Hooshang Hamidian.; Roya Tagizadeh.; Samieh Fozooni.; Vahid Abbasalipour.; Ali Taheri.; Mohadeseh Namjou. Synthesis of novel azo compounds containing 5(4H)-oxazolone ring as potent tyrosinase inhibitors. Bioorganic & Medicinal Chemistry. 2013, 21 (7), 2088-2092 .
Andreas J. Kesel.; Andreas J. Kesel. Broad-spectrum antiviral activity including human immunodeficiency and hepatitis C viruses mediated by a novel retinoid thiosemicarbazone derivative. European Journal of Medicinal Chemistry. 2011, 46 (5), 1656-1664.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant