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5-Amino-2-bromo-3-fluoropyridine, 97% - H33154 - Alfa Aesar

H33154 5-Amino-2-bromo-3-fluoropyridine, 97%

CAS Number

Size Price ($) Quantity Availability
250mg 62.40
1g 173.00
5g 580.00
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5-Amino-2-bromo-3-fluoropyridine, 97%


Chemical Properties

Formula Weight
Melting point


Commercially available 5-bromo-2-fluoropyridine was treated with LDA at -78°C to give the lithiated species. Fluoropyridine-based bromoacetamide reagent has been prepared and used in prosthetic group introduction for the labeling of oligonucleotides.


Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents. Refrigerate(2-7°C ).

Literature References

Bryan W. Stroup,; Paul V. Szklennik,; Cornelia J. Forster,; Michael H. Serrano-Wu.Chemoselective Amination of 5-Bromo-2-chloro-3-fluoropyridine. Org. Lett.,. 2007, 9(10),2039-2042.

Bertrand Kuhnast,; Béatrice de Bruin,; Françoise Hinnen,; Bertrand Tavitia,; Frédéric Dollé .Design and Synthesis of a New [18F]Fluoropyridine-Based Haloacetamide Reagent for the Labeling of Oligonucleotides:? 2-Bromo-N-[3-(2-[18F]fluoropyridin-3-yloxy)propyl]acetamide . Bioconjugate Chem.,. 2004, 15 (3), 617-627.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P260u-P201-P280a-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves and eye/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code


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    1-(4-Methylphenyl)homopiperazine monohydrochloride, 98%
  • H26772

    4-Chloro-3-(trifluoromethoxy)phenol, 97%
  • A10365

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  • J62152

    Sodium phosphate, 0.2M buffer soln., pH 7.4
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    Hydroxylamine, 50% aq. soln.

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