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118078-66-3 - 2-Fluoro-4-(trifluoromethyl)pyridine, 97% - H33198 - Alfa Aesar

H33198 2-Fluoro-4-(trifluoromethyl)pyridine, 97%

CAS Number
118078-66-3
Synonyms

Size Price ($) Quantity Availability
1g 61.44
5g 205.44
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2-Fluoro-4-(trifluoromethyl)pyridine, 97%

MDL
MFCD09879262

Chemical Properties

Formula
C6H3F4N
Formula Weight
165.09
Boiling Point
110°
Solubility
Miscible with water, alcohol, acetonitrile and N,N-dimethylformamide

Applications

2-Fluoro-4-(trifluoromethyl)pyridine acts as a reactant in the preparation of aminopyridines through amination reactions. It is also used as a catalytic ligand for regioselective preparation of tetramethylbiphenyls through aerobic oxidative coupling of xylene catalyzed by palladium.

Notes

Incompatible with oxidizing agents and bases.

Literature References

Pasumansky, L.; Hernández, A. R.; Gamsey, S.; Goralski, C. T.; Singaram, B. Synthesis of aminopyridines from 2-fluoropyridine and lithium amides. Tetrahedron Lett. 2004, 45 (34), 6417-6420.

GHS Hazard and Precautionary Statements

Hazard Statements: H301-H315-H319-H335

Toxic if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P301+P310-P305+P351+P338-P304+P340-P362-P312-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2933.39
TSCA
No

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