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25569-77-1 - 4-Fluorobenzoic anhydride, 97% - H33527 - Alfa Aesar

H33527 4-Fluorobenzoic anhydride, 97%

CAS Number
25569-77-1
Synonyms

Size Price ($) Quantity Availability
1g 81.58
5g 270.89
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4-Fluorobenzoic anhydride, 97%

MDL
MFCD00425938

Chemical Properties

Formula
C14H8F2O3
Formula Weight
262.21
Melting point
111-115°
Sensitivity
Moisture Sensitive
Solubility
Sparingly soluble in water.(0.26 g/L) (25°C),

Applications

It is used as pharmaceutical intermediate. Benzoylthiophenes are allosteric enhancers (AE) of agonist activity at the A1 adenosine receptor.

Notes

Store in cool dry place. Ensure proper ventilation. Incompatible with oxidizing agents.

Literature References

C. Elisabet Tranberg.; Andrea Zickgraf.; Brian N. Giunta.; Henning Luetjens.; Heidi Figler.; Lauren J. Murphree.; Ruediger Falke.; Holger Fleischer.; ? Joel Linden.; Peter J. Scammells.; Ray. A. Olsson. 2-Amino-3-aroyl-4,5-alkylthiophenes:? Agonist Allosteric Enhancers at Human A1 Adenosine Receptors.J. Med. Chem. 2002, 45 (2),382-389 .

Robert H. Dodd.; Catherine Ouannes.; Malka Robert-Gero.; Pierre Potier. Hybrid molecules: growth inhibition of Leishmania donovani promastigotes by thiosemicarbazones of 3-carboxy-.beta.-carbolines.J. Med. Chem. 1989, 32 (6),1272-1276 .

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2916.39
TSCA
No

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