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H33732 4-Methylthiazole-5-sulfonyl chloride, 95%

CAS Number
953070-51-4
Synonyms

Stock No. Size Price ($) Quantity Availability
H33732-MD 250mg 69.30
H33732-03 1g 191.00
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4-Methylthiazole-5-sulfonyl chloride, 95%

MDL
MFCD09864968

Chemical Properties

Formula
C4H4ClNO2S2
Formula Weight
197.66
Melting point
34-36°
Storage & Sensitivity
Moisture Sensitive. Store under Nitrogen. Store at -20°C.
Solubility
Sparingly soluble in water.(0.26 g/L) (25°C),

Applications

It is used as pharmaceutical intermediate. Benzoylthiophenes are allosteric enhancers (AE) of agonist activity at the A1 adenosine receptor.

Notes

Store in cool dry place. Ensure proper ventilation. Incompatible with oxidizing agents.

Literature References

C. Elisabet Tranberg.; Andrea Zickgraf.; Brian N. Giunta.; Henning Luetjens.; Heidi Figler.; Lauren J. Murphree.; Ruediger Falke.; Holger Fleischer.; ? Joel Linden.; Peter J. Scammells.; Ray. A. Olsson. 2-Amino-3-aroyl-4,5-alkylthiophenes:? Agonist Allosteric Enhancers at Human A1 Adenosine Receptors.J. Med. Chem. 2002, 45 (2),382-389 .

Robert H. Dodd.; Catherine Ouannes.; Malka Robert-Gero.; Pierre Potier. Hybrid molecules: growth inhibition of Leishmania donovani promastigotes by thiosemicarbazones of 3-carboxy-.beta.-carbolines.J. Med. Chem. 1989, 32 (6),1272-1276 .

GHS Hazard and Precautionary Statements

Hazard Statements: H314-H335

Causes severe skin burns and eye damage. May cause respiratory irritation.

Precautionary Statements: P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c

Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Hazard Class
8
Packing Group
III
Harmonized Tariff Code
2934.10
TSCA
No

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