Methyl (+/-)-2,2-dimethyl-1,3-dioxolane-4-carboxylate is used as pharmaceutical intermediate.
Yiming Yao; Jim J Lalonde. Unexpected enantioselectivity and activity of penicillin acylase in the resolution of methyl 2,2-dimethyl-1,3-dioxane-4-carboxylate. Journal of Molecular Catalysis B: Enzymatic. 2009, 22 (1-2), 55-59.
Teruhiko Ishikawa; Kazuo Shimizu; Hirokazu Ishii; Shushiro Ikeda and Seiki Saito. Simultaneous Discrimination of Diastereotopic Groups and Faces:? The First Example in Intramolecular [3 + 2] and [2 + 2 + 1] Cycloaddition Reactions.