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5-Bromophthalide is an important organic intermediate. It can be used in agrochemical, pharmaceutical and dyestuff field. It is a key intermediate of citalopram.
Reddy, M Pulla; S, A K; Rao, Bhujanga; Usharani, V; Dubey, P K. Novel and Improved Process for the Preparation of Citalopram. Asian Journal of Chemistry. 2011, 23 (4), 1829-1832.
Dr. Hikaru Yanai; Nobuyuki Ishii; Prof. Dr. Takashi Matsumoto and Prof. Dr. Takeo Taguchi. Organic Acid Catalysts in Reactions of Lactones with Silicon Enolates. Asian Journal of Organic Chemistry. 2013, 2 (11), 989-996.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.