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5-Bromophthalide is an important organic intermediate. It can be used in agrochemical, pharmaceutical and dyestuff field. It is a key intermediate of citalopram.
Reddy, M Pulla; S, A K; Rao, Bhujanga; Usharani, V; Dubey, P K. Novel and Improved Process for the Preparation of Citalopram. Asian Journal of Chemistry. 2011, 23 (4), 1829-1832.
Dr. Hikaru Yanai; Nobuyuki Ishii; Prof. Dr. Takashi Matsumoto and Prof. Dr. Takeo Taguchi. Organic Acid Catalysts in Reactions of Lactones with Silicon Enolates. Asian Journal of Organic Chemistry. 2013, 2 (11), 989-996.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant