Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

H34309 4,5,6,7-Tetrahydrobenzo[b]thiophene, 97%

CAS Number
13129-17-4
Synonyms

Stock No. Size Price ($) Quantity Availability
H34309-MD 250mg 50.90
H34309-03 1g 140.00
H34309-06 5g 469.00
Add to Cart Bulk/Specialty Print Quote View Item

4,5,6,7-Tetrahydrobenzo[b]thiophene, 97%

MDL
MFCD19442759

Chemical Properties

Formula
C8H10S
Formula Weight
138.23
Boiling Point
55°/1mm
Refractive Index
1.5580
Storage & Sensitivity
Air Sensitive. Store under Argon. Ambient temperatures.

Applications

It is an active pharmaceutical intermediate. Condensation of amino carboxyalkyl derivative of 4,5,6,7-tetrahydrobenzo[b]thiophene with salicylaldehyde yielded a potentially tridentate Schiff base (HSAT), which formed a series of copper(II) complexes. Reaction of ethyl 2-diazo-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate 1 with 3-iminobutyronitrile 2 gave the hydrazone derivative.

Notes

Air sensitive. Store at room temperature. Keep container tightly closed in a dry and well-ventilated place.

Literature References

V. Alagarsamy.;S. Meena.; K.V. Ramseshu.; V.R. Solomon.; K. Thirumurugan.; K. Dhanabal.; M. Murugan. Synthesis, analgesic, anti-inflammatory, ulcerogenic index and antibacterial activities of novel 2-methylthio-3-substituted-5,6,7,8-tetrahydrobenzo (b) thieno[2,3-d]pyrimidin-4(3H)-ones. Eur. J. Med. Chem. 2006, 41 (11),1293-1300.

Rafat M. Mohareb,; Fatma M. Manhi. Reaction of ethyl 2-diazo-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate with 3-iminobutyronitrile: synthesis of pyridazines, thiophenes, and their fused derivatives. Heteroatom Chemistry. 2000, 11 (6), 403-412,.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Harmonized Tariff Code
2934.99
TSCA
No

Recommended

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware