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5059-30-3 - 2-Chloroindole-3-carboxaldehyde, 97% - H34381 - Alfa Aesar

H34381 2-Chloroindole-3-carboxaldehyde, 97%

CAS Number
5059-30-3
Synonyms

Size Price ($) Quantity Availability
1g 54.20
10g 332.00
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2-Chloroindole-3-carboxaldehyde, 97%

MDL
MFCD00111620

Chemical Properties

Formula
C9H6ClNO
Formula Weight
179.61
Melting point
ca 212° dec.
Sensitivity
Air Sensitive
Solubility
Slightly soluble in water.

Applications

It is used as pharmaceutical intermediates. It is used in the synthesis of indole phytoalexin cyclobrassinon. And also in unprecedented chemical structure and biomimetic synthesis of erucalexin, a phytoalexin from the wild crucifer Erucastrum gallicum.

Notes

Air sensitive. Store at room temperature.

Literature References

H. D. Hollis Showalter.; Anthony D. Sercel.; Boguslawa M. Leja.; Craig D. Wolfangel.; Linda A. Ambroso.; William L. Elliott.; David W. Fry .; Alan J. Kraker.; Curtis T. Howard.; Gina H. Lu.; Charles W. Moore.; James M. Nelson.; Bill J. Roberts.; Patrick W. Vincent.; William A. Denny.; Andrew M. Thompson. Tyrosine Kinase Inhibitors. 6. Structure-Activity Relationships among N- and 3-Substituted 2,2‘-Diselenobis(1H-indoles) for Inhibition of Protein Tyrosine Kinases and Comparative in Vitro and in Vivo Studies against Selected Sulfur Congeners.J. Med. Chem. 1997, 40 (4),413-426.

Justin R. Harrison.; Christopher J. Moody. The Horner-Wadsworth-Emmons reaction in the synthesis of macrocyclic peptides: the Trp-His-Gly-Arg derived macrocycle of moroidin. Tetrahedron Lett. 2003, 44 (28),5189-5191.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P260u-P201-P280a-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves and eye/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2933.99
TSCA
No

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