Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

52222-73-8 - 4-Trifluoromethyl-1H-pyrazole, 97% - H34396 - Alfa Aesar

H34396 4-Trifluoromethyl-1H-pyrazole, 97%

CAS Number

Size Price ($) Quantity Availability
250mg 195.00
1g 592.00
Add to Cart Add to Quote Request View Item

4-Trifluoromethyl-1H-pyrazole, 97%


Chemical Properties

Formula Weight
Melting point


It is used as pharmaceutical intermediates. The palladium-catalyzed cross-coupling reactions of 5-tributylstannyl-4-fluoro-1H-pyrazole with aryl iodides provided high yields of the corresponding 5-aryl-4-fluoro-1H-pyrazoles.


Incompatible with strong oxidizing agents. Store at room temperature.

Literature References

Takeshi Hanamotoa.; Takao Suetake.; Yukinori Koga.; Toshio Kawanami.; Hiroshi Furuno.; Junji Inanag. Synthesis and reactions of 5-tributylstannyl-4-fluoro-1H-pyrazole.Tetrahedron. 2007, 63 (23), 5062-5070.

Rukkiat Jitchati.; Andrei S. Batsanov.; Martin R. Bryce. N-Arylation of nitrogen heterocycles with 2,4-difluoroiodobenzene. Tetrahedron. 2009, 65 (4), 855-861.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P260u-P201-P280a-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves and eye/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code


  • A10522

    2,3-Dichlorobenzoic acid, 98%
  • 47260

    Potassium, Ion chromatography standard solution, Specpure®, K<sup>+</sup> 1000µg/ml
  • H31332

    2-Methyl-4-nitrobenzoic acid, 97%
  • 43715

    Palladium powder, spherical, APS 0.5-1.7 micron, 99.95% (metals basis)
  • A16155

    Chlorophyllin, coppered trisodium salt

Recently Viewed


Life Science

Metals & Materials


Analytical & Labware