It is employed in fine chemical syntheses and used as pharmaceutical intermediates. A trace of cis-ethoxyacetamide was also detected and isolated with an authentic sample prepared from the reaction of cis-3-amino-6-methylchroman-4-01 (2) with 2-ethoxyacetyl chloride.
Karen K. Bach.; Hesham R. El-Seedi.; Henrik M. Jensen.; Helene B. Nielsen.; Ib Thomsen.; Kurt B.G. Torssell. 1,3-Dipolar cycloadditions of ethoxycarbonyl-nitrile benzylimine, EtOOC C ? Full-size image (<1 K) - Full-size image (<1 K) CH2C6H5, and synthesis of β-amino acids. Synthesis and reactions of ethyl 2-chloro-2-ethoxyacetate and 2-chloro-2-ethoxyacetyl chloride. Tetrahedron. 1994, 50 (25),7543-7556.
Gordon W. Rewcastle.; Hamish S. Sutherland.; Claudette A. Weir.; Adrian G. Blackburn.; William A. Denny. An improved synthesis of isonitrosoacetanilides. Tetrahedron Lett. 2005, 46 (50),8719-8721.
Hazard Statements: H226-H332-H314-H318
Flammable liquid and vapour. Harmful if inhaled. Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P210-P260u-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Do not breathe dusts or mists. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.