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For synthesis and pharmacological evaluation of sulfonamide derivatives of thiazolidin-4-ones 5-Bromo-2-methoxybenzenesulfonyl chloride is used.
Nadeem Siddiqui,; M. Faiz Arshad,; Suroor A. Khana,; Waquar Ahsana. Sulfonamide derivatives of thiazolidin-4-ones with anticonvulsant activity against two seizure models: synthesis and pharmacological evaluation. Journal of Enzyme Inhibition and Medicinal Chemistry. 2010, 25(4),485-491.
Valeria De Matteis,; Floris L. van Delft,; Harald Jakobi,; Stephen Lindell,; Jörg Tiebes,; Floris P. J. T. Rutjes. RCM-Mediated Synthesis of Trifluoromethyl-Containing Nitrogen Heterocycles. J. Org. Chem.,. 2006, 71 (20), 7527-7532.
Hazard Statements: H314-H318
Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P260u-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
Do not breathe dusts or mists. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.