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H36638 3,4-Dihydro-2-(1H)-quinolinone, 98%

CAS Number
553-03-7
Synonyms
Hydrocarbostyril

Stock No. Size Price ($) Quantity Availability
H36638-03 1g 42.20
H36638-06 5g 132.00
H36638-14 25g 440.00
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3,4-Dihydro-2-(1H)-quinolinone, 98%

MDL
MFCD00016722

Chemical Properties

Formula
C9H9NO
Formula Weight
147.18
Melting point
165-167°
Storage & Sensitivity
Light Sensitive. Ambient temperatures.
Solubility
Slightly soluble in water.

Applications

3,4-Dihydro-2-(1H)-quinolinone may be employed as medium supplement in the culture medium of Pseudomonas ayucida during enrichment culture experiments. It is used to prepare potent bicyclic peptide deformylase inhibitors with antibacterial effects. It is also used to synthesize substituted iminopiperidines as inhibitors of human nitric oxide synthase isoforms.

Notes

Light sensitive. Incompatible with oxidizing agents.

Literature References

John J.Kilbane; Rajaram Ranganathan; Lisa Cleveland; Kevin J.Kayser; Claudia Ribiero; Monica M.Linhares. Selective removal of nitrogen from quinoline and petroleum by Pseudomonas ayucida IGTN9m. Appl Environ Microbiol. 2000, 66,(2), 688-693.

Takayuki Tsuritani; Yuhei Yamamoto; Masashi Kawasaki; Toshiaki Mase. Novel approach to 3,4-dihydro-2(1H)-quinolinone derivatives via cyclopropane ring expansion. Organic Letters. 2009, 11,(5), 1043-1045.

 

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H315-H317-H319-H335

Harmful if swallowed. Causes skin irritation. May cause an allergic skin reaction. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P270-P271-P272-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P333+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Rinse mouth. If skin irritation or rash occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Harmonized Tariff Code
2933.49
TSCA
No

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