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3,4-Dihydro-2-(1H)-quinolinone may be employed as medium supplement in the culture medium of Pseudomonas ayucida during enrichment culture experiments. It is used to prepare potent bicyclic peptide deformylase inhibitors with antibacterial effects. It is also used to synthesize substituted iminopiperidines as inhibitors of human nitric oxide synthase isoforms.
John J.Kilbane; Rajaram Ranganathan; Lisa Cleveland; Kevin J.Kayser; Claudia Ribiero; Monica M.Linhares. Selective removal of nitrogen from quinoline and petroleum by Pseudomonas ayucida IGTN9m. Appl Environ Microbiol. 2000, 66,(2), 688-693.
Takayuki Tsuritani; Yuhei Yamamoto; Masashi Kawasaki; Toshiaki Mase. Novel approach to 3,4-dihydro-2(1H)-quinolinone derivatives via cyclopropane ring expansion. Organic Letters. 2009, 11,(5), 1043-1045.
Hazard Statements: H301-H315-H319-H317-H335
Toxic if swallowed. Causes skin irritation. Causes serious eye irritation. May cause an allergic skin reaction. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P301+P310a-P305+P351+P338-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF SWALLOWED: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.