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H36638 3,4-Dihydro-2-(1H)-quinolinone, 98%

CAS Number
553-03-7
Synonyms
Hydrocarbostyril

Stock No. Size Price ($) Quantity Availability
H36638-03 1g 42.20
H36638-06 5g 132.00
H36638-14 25g 440.00
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3,4-Dihydro-2-(1H)-quinolinone, 98%

MDL
MFCD00016722

Chemical Properties

Formula
C9H9NO
Formula Weight
147.18
Melting point
165-167°
Storage & Sensitivity
Light Sensitive. Ambient temperatures.
Solubility
Slightly soluble in water.

Applications

3,4-Dihydro-2-(1H)-quinolinone may be employed as medium supplement in the culture medium of Pseudomonas ayucida during enrichment culture experiments. It is used to prepare potent bicyclic peptide deformylase inhibitors with antibacterial effects. It is also used to synthesize substituted iminopiperidines as inhibitors of human nitric oxide synthase isoforms.

Notes

Light sensitive. Incompatible with oxidizing agents.

Literature References

John J.Kilbane; Rajaram Ranganathan; Lisa Cleveland; Kevin J.Kayser; Claudia Ribiero; Monica M.Linhares. Selective removal of nitrogen from quinoline and petroleum by Pseudomonas ayucida IGTN9m. Appl Environ Microbiol. 2000, 66,(2), 688-693.

Takayuki Tsuritani; Yuhei Yamamoto; Masashi Kawasaki; Toshiaki Mase. Novel approach to 3,4-dihydro-2(1H)-quinolinone derivatives via cyclopropane ring expansion. Organic Letters. 2009, 11,(5), 1043-1045.

 

GHS Hazard and Precautionary Statements

Hazard Statements: H301-H315-H319-H317-H335

Toxic if swallowed. Causes skin irritation. Causes serious eye irritation. May cause an allergic skin reaction. May cause respiratory irritation.

Precautionary Statements: P261-P280a-P301+P310a-P305+P351+P338-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF SWALLOWED: Immediately call a POISON CENTER/doctor IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2933.49
TSCA
No

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