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N-Boc-(methylamino)acetaldehyde is involved in the preparation of benzo[d]imidazole inhibitor of co-activator associated arginine methyltransferase.
Pandya, B. A.; Dandapani, S.; Duvall, J. R.; Rowley, A.; Mulrooney, C. A.; Ryba, T.; Dombrowski, M.; Harton, M.; Young, D. W.; Marcaurelle, L. A. Practical asymmetric synthesis of beta-hydroxy gamma-amino acids via complimentary aldol reactions. Tetrahedron 2011, 67 (34), 6131-6137.
Wan, H.; Huynh, T.; Pang, S.; Geng, J.; Vaccaro, W.; Poss, M. A.; Trainor, G. L.; Lorenzi, M. V.; Gottardis, M.; Jayaraman, L.; Purandare, A. V. Benzo[d]imidazole inhibitors of coactivator associated arginine methyltransferase 1 (CARM1)-hit to lead studies. Bioorg. Med. Chem. Lett. 2009, 19 (17), 5063-5066.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.