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123387-72-4 - N-Boc-(methylamino)acetaldehyde, 98% - tert-Butyl methyl(2-oxoethyl)carbamate - H50870 - Alfa Aesar

H50870 N-Boc-(methylamino)acetaldehyde, 98%

CAS Number
123387-72-4
Synonyms
tert-Butyl methyl(2-oxoethyl)carbamate

Size Price ($) Quantity Availability
250mg 71.90
1g 248.00
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N-Boc-(methylamino)acetaldehyde, 98%

MDL
MFCD08064267

Chemical Properties

Formula
C8H15NO3
Formula Weight
173.21
Sensitivity
Air Sensitive
Solubility
Slightly miscible with water.

Applications

N-Boc-(methylamino)acetaldehyde is involved in the preparation of benzo[d]imidazole inhibitor of co-activator associated arginine methyltransferase.

Notes

Air sensitive. Store in a cool place. Incompatible with strong oxidizing agents.

Literature References

Pandya, B. A.; Dandapani, S.; Duvall, J. R.; Rowley, A.; Mulrooney, C. A.; Ryba, T.; Dombrowski, M.; Harton, M.; Young, D. W.; Marcaurelle, L. A. Practical asymmetric synthesis of beta-hydroxy gamma-amino acids via complimentary aldol reactions. Tetrahedron 2011, 67 (34), 6131-6137.

Wan, H.; Huynh, T.; Pang, S.; Geng, J.; Vaccaro, W.; Poss, M. A.; Trainor, G. L.; Lorenzi, M. V.; Gottardis, M.; Jayaraman, L.; Purandare, A. V. Benzo[d]imidazole inhibitors of coactivator associated arginine methyltransferase 1 (CARM1)-hit to lead studies. Bioorg. Med. Chem. Lett. 2009, 19 (17), 5063-5066.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2924.19
TSCA
No

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