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873-73-4 - 4-Chlorophenylacetylene, 98% - 1-Chloro-4-ethynylbenzene - H51058 - Alfa Aesar

H51058 4-Chlorophenylacetylene, 98%

CAS Number
873-73-4
Synonyms
1-Chloro-4-ethynylbenzene

Size Price ($) Quantity Availability
1g 152.44
5g 510.78
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4-Chlorophenylacetylene, 98%

MDL
MFCD00191917

Chemical Properties

Formula
C8H5Cl
Formula Weight
136.58
Melting point
43-47°
Boiling Point
179°
Flash Point
57°(135°F)
Solubility
Insoluble in water. Soluble in acetone, chloroform, dichloromethane, DMF, DMSO, ethanol, ethyl acetate, hexane, methanol,THF and toluene.

Applications

4-Chlorophenylacetylene is used as pharmaceutical intermediate.

Notes

Stable under recommended storage conditions. Incompatible with oxidizing agents.

Literature References

Andrew G.Firth; Ian J.S.Fairlamb; Kate Darley; Christoph G.Baumann. Sonogashira alkynylation of unprotected 8-brominated adenosines and guanosines: fluorescence properties of compact conjugated acetylenes containing a purine ring. Tetrahedron Letters. 2006, 47, (21),3529-3533

 

Dawei Ma; Feng Liu. CuI-catalyzed coupling reaction of aryl halides with terminal alkynes in the absence of palladium and phosphine. Chem. Commun. 2004, (17),1934-1935

GHS Hazard and Precautionary Statements

Hazard Statements: H228-H319-H335

Flammable solid. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P305+P351+P338

IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Other References

Hazard Class
4.1
Packing Group
III
Harmonized Tariff Code
2903.99
TSCA
No

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