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1-Aza-15-crown-5 is used as building block for the synthesis of bis-crown ethers, lariat ethers and other monofuctionalized macrocycles. It is also used as pharmaceutical intermediate.
Pu Qian; Toshiro Yokoyama; Osamu Itabashi; Tomio Goto; Tokuji Miyashita. Ag+ ion sensing by the polymer Langmuir-Blodgett films containing 1-aza-15-crown 5-ether group. Thin Solid Films. 1997, 305, (1-2),316-320
Kh. A.Hassan. Spectroscopic studies of complexes of iodine with the bases 1-aza-15-crown-5 and 3,6,9,14-tetrathiabicyclo[9.2.1]tetradeca-11,13-diene. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2004, 60, (13),3059-3063
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.