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Isopropyl magnesium chloride is used primarily to add an iso-propyl group to carbonyl groups. This reagent can also be used as a strong base in aprotic solvents.
Shimpei Sugiyama; Hitomi Shimizu; Tsuyoshi Satoh. The first example of γ-chloromagnesio γ-lactones: their generation from γ-tolylsulfinyl γ-lactones with isopropylmagnesium chloride, stability, and reaction with electrophiles. Tetrahedron Letters. 2006, 47, (49),8771-8775
Juan de M.Munoz; Jesus Alcazar; Antonio de la Hoz; Angel Diaz-Ortiz; Sergio-A. Alonso de Diego. Preparation of amides mediated by isopropylmagnesium chloride under continuous flow conditions. Green Chem. 2012, 14, (5),1335-1341
Hazard Statements: H225-H261-H314-H318
Highly flammable liquid and vapour. In contact with water releases flammable gas. Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P223-P210-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from any possible contact with water, because of violent reaction and possible flash fire. Keep away from heat/sparks/open flames/hot surfaces. - No smoking. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.